Importance Of Stent Coatings

Importance Of Stent Coatings – Drug-eluting Stent Coatings – Cheersonic

In-stent restenosis remains unacceptably high in some high-risk patients and late stent thrombosis has been a major concern associated with current clinical applications of drug-eluting stents. Therefore, a number of studies have addressed these problems through modification of the stent with respect to the blood and tissue compatibility, including changing the stent material itself and modifying the outer layer of the stent surface, aggressive anticoagulant and antiplatelet therapies, or antiproliferative strategies to inhibit neointimal growth. While some materials with excellent mechanical properties have no favorable biocompatibility, other materials with good biocompatibility are not suitable for stent production. Thus, modifying or coating different materials on the stent surface is one of the effective methods to alter characteristics of the stent surface and improve the stent’s biocompatibility and hemocompatibility, and hence reduce the occurrence of thrombosis and restenosis.