Coat Drug-Eluting Balloons
Coat Drug-Eluting Balloons – Ultrasonic Coating – Cheersonic
Drug-Eluting Balloons may stand for an alternative to Drug-Eluting Stents in some clinical situations. The rationale for the development of Drug-Eluting Balloons derives mainly from the limitations of Drug-Eluting Stents. The initial enthusiasm for reducing the incidence of restenoses after Drug-Eluting Stent was weakened by reports indicating the risk of late-thrombosis after antimitotic drug-releasing stents. Although certainly, for many years, Drug-Eluting Stent will remain an essential tool in the treatment of coronary artery disease, it should not be forgotten that their use is not entirely effective and safe. Apart from the risk mentioned above of thrombosis, the phenomenon of restenosis cannot be ignored.
Drug-Eluting Balloons ensure even distribution of the drug for a short period of balloon inflation and contact with the vessel wall and do not increase the risk of chronic inflammatory reaction. Despite the differences in the construction of individual balloons, they share common features. In Drug-Eluting Balloon systems, mainly lipophilic drugs are used for better tissue absorption, which shortens the time to fill the balloon and extends the effect after emptying, preventing the premature flushing out of the active substance.
Ultrasonic Balloon Catheter Coating System is suited to coating high pressure medical balloons with drug eluting polymers such as Paclitaxel and other bioabsorbable drugs for dilation procedures including coronary angioplasty or stent delivery applications.
The Balloon Catheter Coating System is a fully enclosed, sealed glovebox unit designed to coat common sizes and types of balloon catheters using Cheersonic ultrasonic nozzles combined with our UAM7000 precision air shaping systems. The spray pattern diameter and drop size are variable, depending upon the nozzle and air shaping system used. A proprietary holding device secures both ends of the catheter while rotational motors spin the catheter for 360Ocoverage of the entire balloon surface. The ultrasonic nozzle traverses across the catheter as required to coat desired lengths. The system includes controls for air flow rate, air pressure as well as continuous digital metering of humidity and temperature.
